BRP is my favorite. The rules are simple and easy to learn (I seriously have everything memorized except for some optional rules) and it's really easy to implement new/homebrewed mechanics without breaking the game. I also like that size is an actual stat instead of some abstract size class (how much bigger than me is that Dragon?). If you want some semblance of realism, BRP is the system to use.
I also like how combat in the system has to be dealt with tactically: Player Hit points are low, big things have more hit points and do more melee damage. I know gritty, tactical combat isn't for everybody, but I personally love it.
BRPs biggest flaw is that it can be a bit math heavy. You have to calculate Hit Point, Derived Stats, Damage Bonuses, Stat Bonuses (if you're using that optional rule), and dynamic Critical/Special/Fumble ranges (if you're using that optional rule, but why wouldn't you?).
d20 Modern was really restrictive and, like most d20 based systems, really unstable.
GURPS is WAY too complicated and counter intuitive. I've never seen a GURPS game that did not have every player constantly with their nose in the book trying to figure out how to do some mundane action. Plus the vehicle rules are wonky.
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