How about "Sparks" from Girl Genius, pushed forward to the present day?
Imagine a few "mad scientist" mutants who invent technologies ordinary humans can't fathom, which might as well work via magic. Do they stay in their laboratories inventing? Do they take over the world? What's with the mad cackling?
Yes they might invent star drives that cause ordinary humans to go mad, yes they invent cloning vats that churn out impressionable child-men to use as spare parts, yes their Universal Robots sometimes go berserk and their flying cars are a menace to the airways ... but we can't allow a Mad Scientist Gap! Plus, they have death rays.
(This is partly tongue-in-cheek, but Philip K. Dick's Our Friends from Frolix-8 did in fact posit super-genius mutants who became de-facto rulers of the solar system through super-advanced technology. As does Watchmen via Dr. Manhattan.)
If you prefer, we can posit an alien race that descends from the stars to give mankind technological marvels beyond their understanding. But what's their real agenda? What happens to those who uncover the truth? And what's the title of the mysterious book the ambassador left behind?
"On two occasions I have been asked [by members of Parliament], 'Pray, Mr. Babbage, if you put into the machine wrong figures, will the right answers come out?' I am not able rightly to apprehend the kind of confusion of ideas that could provoke such a question."
- Charles Babbage (1791 - 1871)