I've done Changeling LARPs, Orpheus (which I adored), a little Scion, tons of D&D 3.5, and have now gotten the ropes of D&D 4e. If I could play every night of the week, I would. Personally, I prefer smaller groups, but I know that's not always an option.
Online, I only do one on one role plays, but I'm open to nearly any setting so long as there is some fantasy element to it.
I typically work Tuesdays, Fridays, and Sundays, plus already have a sanctioned game on Wednesdays, but the rest of my work schedule is up in the air. If you have a game on a specific night, let me know and I'll see if I can work my schedule around it.